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目的:探讨呼出气一氧化氮(FeNO)检测在哮喘-慢性阻塞性肺疾病重叠综合征(ACOS)患者中的意义和临床价值。方法:选取49例老年ACOS患者为A组,49例慢性阻塞性肺疾病患者为B组,49例哮喘患者为C组,49例健康人为D组,对四组患者的FeNO检测值进行对比分析。结果:A组患者的FeNO检测值明显高于B组及D组(P<0.05),明显低于C组(P<0.05)。A组患者的FeNO增高率明显高于B组、D组(P<0.05),与C组差异无统计学意义(P>0.05)。结论:在老年ACOS的临床诊断上,FeNO的应用价值相对较高,可对老年患者的气道炎症进行科学准确的评估。
Objective: To investigate the significance and clinical value of exhaled nitric oxide (FeNO) detection in patients with asthma - chronic obstructive pulmonary disease overlap syndrome (ACOS). Methods: Forty-nine elderly patients with ACOS were selected as group A, 49 patients with chronic obstructive pulmonary disease as group B, 49 patients with asthma as group C, and 49 healthy people as group D. FeNO values were compared between the four groups . Results: FeNO in group A was significantly higher than that in group B and group D (P <0.05), but significantly lower than that in group C (P <0.05). The increase rate of FeNO in group A was significantly higher than that in group B and group D (P <0.05), but there was no significant difference between group A and group C (P> 0.05). Conclusion: The clinical value of FeNO is relatively high in the clinical diagnosis of elderly patients with ACOS. It can be used to evaluate the airway inflammation in elderly patients scientifically and accurately.