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敏乐啶(minoxidil)是一种强效血管扩张剂,能直接松弛血管平滑肌,对严重高血压有明显疗效。由于其扩血管作用,该药可以增加心输出量和改善左室功能。本研究评价敏乐啶治疗严重慢性充血性心力衰竭的血液动力学和长程临床疗效。方法 11例慢性充血性心衰患者,年龄43~76(平均55)岁。10例缺血性心脏病,1例为不明原因的心肌病。所有患者均有左、右心室衰竭的体征,肺高
Minoxidil is a potent vasodilator that directly relaxes vascular smooth muscle and has a significant effect on severe hypertension. Due to its vasodilator action, the drug increases cardiac output and improves left ventricular function. This study evaluated the hemodynamic and long-term clinical effects of minoxidil in the treatment of severe chronic congestive heart failure. Methods 11 patients with chronic congestive heart failure, aged 43 to 76 (mean 55 years). 10 cases of ischemic heart disease, 1 case of unexplained cardiomyopathy. All patients had signs of left and right ventricular failure, lung height