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作者在本文中对1945～1985年间收治的1400例结直肠腺癌病人重点回顾其临床表现,癌肿的解剖部位和分期对预后的影响.全组病人女812例(58%),男588例(42%).发现癌肿的中值年龄为70岁,50～79岁的病人占75%,小于40岁者占5%.癌肿位于直肠乙状结肠处者占68%,但在最近300例病人中此处癌肿仅为53%,表明右结肠癌的发病率增高.全组病人中直肠癌最常见(35%),其次为乙状结肠癌(30%)、盲肠癌(13%)和升结肠癌(7%).出血是最常见的临床表现(53%),其次为疼痛(19%)、排便改变(15%)和梗阻(7%).腹部有肿物或常规体检时发现癌肿病人的5年存活率最高,分别为38%和50%,而出血、疼痛、排便改变和梗阻者则分别为27%、25%、29%和13%.各部位癌肿的5年存活率无差别.
In this article, the author reviewed 1400 patients with colorectal adenocarcinoma who were admitted to hospital from 1945 to 1985. The clinical manifestations, the anatomical sites of cancer, and the effect of staging on the prognosis were reviewed. 812 women (58%) and 588 men (42%). The median age of cancer was found to be 70 years old, 75% of patients 50 to 79 years old, and 5% of those less than 40 years old. 68% of cancers located in rectal sigmoid colon, but in the last 300 cases In this patient, the cancer was only 53%, indicating an increase in the incidence of right colon cancer. The rectal cancer was most common in the whole group (35%), followed by sigmoid colon cancer (30%), colorectal cancer (13%), and liters. Colon cancer (7%). Hemorrhage is the most common clinical manifestation (53%), followed by pain (19%), defecation change (15%) and obstruction (7%). Cancer was found on the abdomen with a tumor or a routine physical examination. Swollen patients had the highest 5-year survival rates of 38% and 50%, respectively, while bleeding, pain, bowel changes, and obstruction were 27%, 25%, 29%, and 13%, respectively. There is no difference in rates.