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目的了解咸宁市正常人群及血吸虫疫区人群乙肝病毒(HBV)基因型分布状态。方法取正常体检人员和血吸虫疫区例行体检人员中筛选出的HBsAg阳性携带者血清,用槽式PCR技术进行乙肝病毒基因分型检测。结果 86份HBsAg阳性血清标本(正常和血吸虫疫区人群分别43例)中检出B型69份(80.23%)、BC型10份(11.62%)、C型4份(4.65%)。结论咸宁地区正常人群感染HBV基因型均为B型,血吸虫疫区人群感染HBV基因型以B型为主,其次为C型、BC混合感染型。
Objective To understand the distribution of hepatitis B virus (HBV) genotypes in normal population and schistosomiasis in Xianning city. Methods Serum of HBsAg positive carriers screened from the regular physical examination staff and routine medical staff of the schistosomiasis epidemic area were tested by genotyping with the trough PCR technique. Results Among the 86 HBsAg positive serum samples, 43 (80.23%) were type B, 10 (11.62%) were BC and 4 (4.65%) were C type. Conclusion The HBV genotypes of normal population in Xianning are all B genotype. The genotypes of HBV in the infected area of schistosomiasis are mainly B genotype, followed by C genotype and BC genotype.