Monitoring drilling deviation is important for drilling of boreholes and measuring injection rock permeability by Lugeon value for safe and efficient drilling and grouting. This paper is aiming at the study drilling deviation and relationship between drilling and injection permeability at the depth of 100 m in dam of Pushi River. The results show that at different depths the deviation of grouting borehole is within the allowable range according to specifications. LU value decreases with the depth increased in general, but at the depths between 40-41 m the permeability is 1.5 LU, and at 24 m the LU value is the largest (2 LU) in this site by this study. The study thus concludes that even though the rocks are hard and their injection permeability decreases with depth increased, good drilling practices including carefully considering technical and geological specifications can get good drilling boreholes. Monitoring drilling deviation is important for drilling of boreholes and measuring the injection rock permeability by Lugeon value for safe and efficient drilling and grouting. This paper is aiming at the study drilling deviation and relationship between drilling and injection permeability at the depth of 100 m in dam of Pushi River. The results show that at different depths the deviation of grouting borehole is within the allowable range according to specifications. LU value decreases with the depth increased in general, but at the depths between 40-41 m the permeability is 1.5 LU, and at 24 m the LU value is the largest (2 LU) in this site by this study. The study therefore concludes that even though the rocks are hard and their injection bend resistance decreased with depth increased, good drilling practices including carefully consulting technical and geological specifications can get good drilling boreholes.