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目的探讨 rh BMP- 2 /胶原 /珊瑚复合人工骨临床应用的骨修复能力。方法将 rh BMP- 2 /胶原 /珊瑚复合人工骨植入阻生智齿拔除后的牙槽窝内 ,并设单纯珊瑚和空白对照组 ,术后进行临床和 X线检查 ,记录邻近的第二磨牙远中牙槽嵴的高度和第二磨牙的松动度。结果术后 12周复合骨组牙槽窝骨缺损和牙槽嵴高度均得到良好的恢复 ,珊瑚骨组得到较好的恢复 ,而空白对照组结果不明显。结论 rh BMP- 2 /胶原 /珊瑚复合人工骨植入智齿牙槽窝可较好的修复牙槽窝骨缺损。这种新型的复合骨可能是临床应用的一种较理想的生物性植骨材料。
Objective To investigate the bone repair ability of rh BMP-2 / collagen / coral artificial bone. Methods The rh BMP-2 / collagen / coral composite artificial bone was implanted into the alveolar fossa after removal of impacted wisdom tooth, and pure coral and blank control group were set up. Clinical and X-ray examination was performed after operation, and the adjacent second molars The height of the alveolar ridge and the degree of loosening of the second molars. Results The alveolar bone defect and alveolar ridge height were recovered well in composite bone group at 12 weeks after operation, and the coral bone group recovered well, while the blank control group showed no obvious effect. Conclusion rh BMP-2 / collagen / coral composite artificial bone implanted in the wisdom tooth socket can better repair the alveolar defect. This new composite bone may be a more ideal biomaterial for clinical application.