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MDS-AML 是由骨髓增生异常综合征(MDS)转化而来的急性髓性白血病(AML)。有人提出大多数AML 发生前都有过临床症状不明显的白血病前期(MDS),然而尚未有实验室指标来区分MDS-AML和原发性AML(指未有过MDS 或以前未用过诱变剂治疗的AML)。本文旨在研究外周血多形核白细胞形态是否能用于鉴定原发性AML 亚群,其异常改变与MDS 相同。
MDS-AML is acute myelogenous leukemia (AML) that is transformed by myelodysplastic syndrome (MDS). It has been suggested that prior to the onset of most AML, there are pre-clinical stages of preleukemia (MDS) with no clinically significant symptoms. However, laboratory tests have not been available to distinguish between MDS-AML and primary AML (those that have not had MDS or have not been previously used) AML). This article aims to study whether the morphology of peripheral blood polymorphonuclear leukocytes can be used to identify the primary AML subgroup, the abnormal changes and MDS the same.