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目的:通过对24例注射清开灵注射液引起的不良反应进行分析,探讨其在临床中的合理应用。结果:在24例患者中,有9例患者在给药后20 min内即出现不良反应,占37.5%,有7例在给药后的1 h内出现不良反应,占29.17%,有5例在给药1 h后出现不良反应,占20.83%,另外3例在给药3 d后出现不良反应。在24例患者中有11例患者有药物热反应,有10例患者出现皮肤反应,有3例出现过敏性休克。结论:医护人员应严格掌握清开灵注射液适应证、禁忌证、配伍禁忌及使用方法,加强用药监护,力求合理、规范、安全用药,减少不良反应的发生率。
Objective: To analyze the adverse reactions caused by injection of Qingkailing injection in 24 cases and discuss its reasonable application in clinic. Results: Among the 24 patients, 9 patients showed adverse reactions within 20 min after the administration, accounting for 37.5%. Seven patients showed adverse reactions within 1 h after administration, accounting for 29.17%, and 5 patients Adverse reactions occurred after 1 h administration, accounting for 20.83%. The other 3 patients showed adverse reactions after 3 d administration. Eleven of the 24 patients had a thermodynamic drug response, 10 had a skin reaction, and 3 had anaphylactic shock. Conclusion: Medical staff should strictly control the indications, contraindications and contraindications of Qingkailing injection, strengthen the supervision of medication, and strive to reasonable, standardized and safe medication to reduce the incidence of adverse reactions.