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目的探讨短期小剂量糖皮质激素对儿童支原体肺炎(MPP)的临床治疗效果。方法 MPP患儿60例随机分组,对照组30例单纯应用阿奇霉素治疗,研究组30例联合应用阿奇霉素和糖皮质激素琥珀酸氢化考的松,观察两组出院前血沉、CRP、临床不良症状消失时间、发热持续时间等指标。结果研究组血沉水平、CRP水平、临床不良症状消失时间和发热持续时间明显低于对照组,差异有统计学意义(P<0.01)。结论短期小剂量应用糖皮质激素配合抗生素治疗儿童支原体肺炎较单纯应用抗生素具有更好的临床疗效,可提高患儿呼吸系统组织损伤的修复效果,缩短住院时间。
Objective To investigate the clinical effect of short-term low-dose glucocorticoids on mycoplasma pneumonia (MPP) in children. Methods A total of 60 children with MPP were randomly divided into control group (n = 30) and azithromycin (n = 30). The study group was treated with azithromycin and glucocorticoid hydrogenated cortisone succinate respectively. Erythrocyte sedimentation rate, CRP, disappearance of clinical adverse symptoms , Duration of fever and other indicators. Results The level of erythrocyte sedimentation rate, CRP level, disappearance time of clinical adverse symptoms and duration of fever in the study group were significantly lower than those in the control group (P <0.01). Conclusion Short-term low-dose glucocorticoid with antibiotics in children with mycoplasma pneumonia than the simple application of antibiotics has better clinical efficacy, can improve children’s respiratory tissue damage repair effect and shorten the hospital stay.