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目的探讨卡前列素氨丁三醇治疗孕产妇产后出血的临床疗效。方法选取2013年4月至2015年4月收治的产后出血患者102例,随机分为两组,每组51例。对照组给予缩宫素治疗,观察组同时采用缩宫素与卡前列素氨丁三醇治疗,比较两组产妇的止血效果、止血时间、产后24 h出血量、止血满意度以及不良反应发生情况。结果 1观察组产后24 h出血量少于对照组,止血时间短于对照组,差异有统计学意义(P<0.05)。2观察组止血总有效率为96.08%,对照组为74.51%,差异有统计学意义(P<0.05)。3观察组的止血满意度为96.08%,对照组为72.55%,差异有统计学意义(P<0.05)。4观察组不良反应发生率为3.92%,对照组为5.88%,差异未见统计学意义(P>0.05)。结论卡前列素氨丁三醇能够被应用于孕产妇产后出血的治疗中,安全性较高,值得临床推广。
Objective To investigate the clinical efficacy of carboprost trometamol in the treatment of postpartum hemorrhage. Methods A total of 102 postpartum hemorrhage patients who were admitted from April 2013 to April 2015 were randomly divided into two groups (51 in each group). The control group was treated with oxytocin. The observation group was treated with oxytocin and carboprost trometamol at the same time. The hemostatic effect, bleeding time, blood loss at 24 h postpartum, hemostasis satisfaction and adverse reactions were compared between the two groups . Results 1 The observation group 24 h postpartum bleeding less than the control group, bleeding time shorter than the control group, the difference was statistically significant (P <0.05). 2 The observation group, the total effective rate of 96.08% to stop bleeding, the control group was 74.51%, the difference was statistically significant (P <0.05). 3 The hemostasis satisfaction of the observation group was 96.08%, while the control group was 72.55%, the difference was statistically significant (P <0.05). The incidence of adverse reactions in the observation group was 3.92% and in the control group was 5.88%, the difference was not statistically significant (P> 0.05). Conclusion Carprost trometamol can be used in the treatment of postpartum hemorrhage, which is safe and worthy of clinical promotion.