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正常胃内基本上是无菌的,但在胃内酸度或动力发生变化时,则可引起细菌生长,使术后感染机会升高.近年来由于采用组胺H_2-受体拮抗剂而使消化性溃疡的治疗有了改观,其中应用最为广泛的甲氰咪胍,能有效地降低酸度及分泌,当用治疗剂量时可将胃内pH值提高到3以上.为了解甲氰咪胍对胃内菌群生态的影响,作者选择了20例因消化性溃疡而拟行胃大部切除的病人进行分析.病史及手术指征相仿,均曾接受过包括4周～6月(平均10周)的甲氰咪胍
The normal stomach is basically sterile, but when the gastric acidity or motility changes, it can cause bacterial growth, so that the chance of infection after surgery increased in recent years due to histamine H 2 -receptor antagonist digestion The treatment of ulcer has changed, of which the most widely used cimetidine, can effectively reduce the acidity and secretion, when the therapeutic dose can increase the intragastric pH to 3. In order to understand the influence of cimetidine on the stomach The author selected 20 patients due to peptic ulcer to be gastrectomy patients analyzed.History and operation indications are similar, have been accepted, including 4 weeks to 6 months (an average of 10 weeks) Of cimetidine