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将小鼠器官块移植至其腹腔扩散盒内可存活5天,心脏比肾脏易于存活。人鼻咽癌细胞株与小鼠器官接触培养6小时后,瘤细胞开始紧贴于器官块表面,以丝状伪足或微绒毛与器官细胞相连接,然后伸出伪足开始向内侵入;24小时后可侵袭到器官细胞实质内;3天后器官细胞出现变性及轻度坏死,但瘤细胞仍存活良好。瘤细胞形成巢样结构,少数出现核分裂相,说明瘤细胞有繁殖的趋势。
Transplantation of the mouse organ block into its peritoneal diffusion box can survive for 5 days and the heart is easier to survive than the kidneys. Human nasopharyngeal carcinoma cell lines and mouse organ culture contact 6 hours after the tumor cells began to cling to the surface of the organ, with filopodia or microvilli connected with the organ cells, and then extend the pseudo-foot began inward invasion; After 24 hours, it could invade the parenchyma of the organ cells. After 3 days, the organ cells degenerated and mild necrosis, but the tumor cells still survived well. Neoplastic cells form nests, a small number of mitotic phase, indicating that the tumor cells have the tendency to reproduce.