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观察了α_1型基因工程干扰素治疗尖锐湿疣分别用皮损内注射和肌肉注射治疗17例和13例的疗效对比,每次100万u,3周内共9次。皮损注射组痊愈4例(23.6%),显效7例(41.2%),有效和无效各3例(17.6%)。肌肉注射组痊愈和显效各1例,有效3例,无效8例。结果显示前者疗效优于后者(P<0.01)。皮损注射组出现副作用7例(41.2%),主要为乏力等流感样症状。
The therapeutic effects of α_1 genetically engineered interferon in the treatment of condyloma acuminatum were compared between 17 cases and 13 cases treated with intradermal injection and intramuscular injection respectively, 1 million u each and 9 times within 3 weeks. Lesions in the injection group were cured in 4 cases (23.6%), markedly effective in 7 cases (41.2%), effective and ineffective in 3 cases (17.6%). Intramuscular injection group cured and effective in 1 case, effective in 3 cases, 8 cases. The results show that the former is better than the latter (P <0.01). There were 7 cases (41.2%) of the side effects in the skin lesion injection group. The main symptoms were flu-like symptoms such as fatigue.