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TNF-α主要由单核/巨噬细胞,Th_1细胞产生;具有促进T、B细胞增殖、分化、抗炎、抗肿瘤等多种生物学活性。文献报导新生儿单核细胞产生TNF-α水平低下,但其机理尚不清楚。本文
TNF-α is mainly produced by monocytes / macrophages and Th_1 cells; it has many biological activities such as promoting T, B cell proliferation, differentiation, anti-inflammation and anti-tumor. Reported in the literature of neonatal mononuclear cells produce low levels of TNF-α, but the mechanism is unclear. This article