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作者为探索老年人(≥70岁)多发性骨髓瘤(MM)积极化疗的可行性,研究110例有症状的或进展性MM,非随机地选用年轻患者使用的化疗方案.临床按Durie和Salmon分期,治疗组间有充分的可比性.MOCCA组(68例):马法兰0.25mg/kg口服第1-4天,长春新碱0.03mg/kg静注第1天,环磷酰胺10mg/kg静注第1天,
In order to explore the feasibility of aggressive chemotherapy for multiple myeloma (MM) in the elderly (≥70 years), we investigated the chemotherapeutic regimen of 110 young patients with symptomatic or advanced MM, who were not randomized.They were randomly divided into Durie and Salmon The patients in the MOCCA group (68 cases) were treated with melphalan 0.25 mg / kg orally for 1-4 days, vincristine 0.03 mg / kg on day 1, cyclophosphamide 10 mg / kg Note on the first day,