为探讨母乳中生长抑素的存在、变化规律及作用,应用放射免疫法系列观测30名正常哺乳产妇乳汁及相对应的血浆中生长抑素水平。结果:母乳生长抑素水平3倍～4倍于母血。母乳中该激素水平自产后7天起持续显著下降(P均<0.05),至产后3月其变化趋于平缓。结果表明,母乳中高浓度的生长抑素极可能有助于维持新生儿消化机能平衡;降低哺乳妇女乳腺癌发病率。 In order to explore the existence, variation and role of somatostatin in breast milk, the levels of somatostatin in the milk and corresponding plasma of 30 normal breastfeeding women were observed by radioimmunoassay. Results: The level of somatostatin in breast milk was 3 times to 4 times that of maternal blood. The level of hormones in breast milk continued to decline significantly from the 7th day after delivery (all P <0.05), and its change tended to be gentle until March after delivery. The results show that high concentrations of somatostatin in breast milk most likely contribute to maintaining neonatal digestive balance; reduce the incidence of breast cancer in lactating women.