淋巴细胞性垂体炎(lymphocytic hypophysitis,LHP)是到目前为止人类发现最晚的一种自身免疫性内分泌疾病,以垂体淋巴细胞浸润为特征,多见于妊娠后期或产后年轻妇女。临床表现类似垂体肿瘤,有头痛、视力下降和垂体功能减退。自1962年Goudie和Pinkerlon报道3例在尸检标本中证实的淋巴细胞性垂体炎,迄今已超过145例,国内报道4例,1例有病理诊断。实际上其发病率远高于文献报道,主要因为对本病的认识不足,以及缺乏可靠的诊断依据。本文 Lymphocytic hypophysitis (LHP) is by far the most recently discovered human autoimmune endocrine disease, characterized by pituitary lymphocyte infiltration, more common in post-pregnancy or postpartum young women. Clinical manifestations similar to pituitary tumors, headache, decreased vision and hypopituitarism. Since 1962 Goudie and Pinkerlon reported 3 cases of autopsy specimens confirmed lymphocytic hypophysitis, so far has been more than 145 cases, 4 cases reported in China, 1 case of pathological diagnosis. In fact its incidence is much higher than reported in the literature, mainly because of lack of understanding of the disease, and the lack of reliable basis for diagnosis. This article