以Ｌ－谷氨酰胺为手性选择剂，建立了对普萘洛尔、慢心律、心律平、苯丙哌酮、异丙肾上腺素、氯胺酮、山莨菪碱、洛贝林、布比卡因、苯海索等１０种手性药物对映体的毛细管电泳快速分离方法，在含有６０ｍｍｏｌ／Ｌ Ｌ－谷氨酰胺，６０ｍｍｏｌ／Ｌ硼砂（ｐＨ＝９．２５）的缓冲溶液中，１０种手性药物在１１ｍｉｎ内达到基线分离。并对分离机理作了初步探讨。 L-glutamine was used as a chiral selective agent to establish the effect of propranolol, slow heartbeat, cardioversion, beraprost, isoprenaline, ketamine, anisodamine, lobeline, bupivacaine , Phenoxybenzaldehyde and other 10 kinds of chiral drugs by capillary electrophoresis rapid separation method, containing 60mmol / L L-glutamine, 60mmol / L borax (pH = 9.25) buffer solution, 10 kinds of hands Sex drugs reached baseline separation within 11 min. The mechanism of separation was also discussed.