论文部分内容阅读
目的 :研究己酮可可碱 (Pentoxifyline,PTF)对弱精患者精子活力的影响 ,探讨 PTF提高精子活力的作用机理。方法 :采用计算机辅助精子分析 (CASA)系统 ,以同一份精液标本为自身对照 ,测定 PTF处理前后精子活力参数值。结果 :PTF处理后精子活力 (a+b级 )显著提高 (P<0 .0 1) ,对提高快速前向运动精子活力 (a级 )有极显著意义 (P<0 .0 0 5 ) ,而对精子活动率的提高不显著 (P>0 .0 5 ) ;PTF对活动力较好精子活力的提高不及活动力差的明显 (P<0 .0 5 )。结论 :PTF能有效提高弱精患者精子活力
OBJECTIVE: To study the effect of Pentoxifyline (PTF) on sperm motility in asthenospermia patients and to explore the mechanism of PTF in enhancing sperm motility. Methods: The computer assisted sperm analysis (CASA) system was used to compare the sperm motility parameters before and after treatment with the same sperm sample as the self-control. Results: The sperm motility (a + b) significantly increased (P <0.01) after PTF treatment, and it was significantly (P <0.05) significant for improving the motility of fast motile sperm While the sperm motility did not increase significantly (P> 0.05). The PTF activity of sperm improved less than that of sperm motility (P <0.05). Conclusion: PTF can effectively improve sperm motility in patients with weak essence