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前列腺疾病与细胞增殖及凋亡的状态有密切关系。Bcl 2 /Bax是决定细胞凋亡抑制作用强弱的极重要基因 ,Fas/FasL同为细胞死亡因子 ,在介导细胞凋亡中起重要作用。本文就细胞增殖及凋亡状态及Bcl 2 /Bax、Fas/FasL基因调控与前列腺疾病的关系及展望作一综述。
Prostate disease and cell proliferation and apoptosis are closely related to the state. Bcl 2 / Bax is a very important gene that determines the effect of apoptosis inhibition. Fas / FasL is a cell death factor and plays an important role in mediating apoptosis. This review summarizes the relationship between cell proliferation and apoptosis, the regulation of Bcl 2 / Bax, Fas / FasL gene and prostatic diseases.