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恶性肿瘤晚期可广泛转移至机体几乎所有器官 ,但骨骼肌转移瘤占所有恶性肿瘤血源性转移的1%以下 ,多数尸解报道亦提示骨骼肌内很少发现转移瘤生长 ,即使见到转移瘤亦为数稀少。上述现象与骨骼肌占机体比重大、其血流丰富相矛盾 ,提示骨骼肌对肿瘤转移极具抵御性。骨骼肌可能通过自分泌和 /或旁分泌形式产生某种 (些 )能够显著抑制肿瘤细胞生长的低分子量细胞因子 ,即骨骼肌源性抑瘤物 ,从而导致了骨骼肌转移瘤的罕见性
Late malignant tumors can be widely transferred to almost all organs of the body, but skeletal muscle metastases account for less than 1% of all malignant tumors of blood-borne metastases, the majority of autopsy reports also suggest that skeletal muscle rarely found in the growth of metastases, even if the transfer is seen Tumors are also rare. The above phenomena and skeletal muscle account for a large proportion of the body, the blood flow is contradictory, suggesting that skeletal muscle highly resistant to tumor metastasis. Skeletal muscle may produce some (or some) low-molecular-weight cytokines that can significantly inhibit the growth of tumor cells, ie, skeletal myxomas, through autocrine and / or paracrine forms, leading to the rare property of skeletal muscle metastases