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乙型肝炎病毒(HBV)与原发性肝癌之间的关系已被公认,很多研究证实在肝癌细胞内及肝外多种组织细胞内均有HBV DNA的存在。这对HBV肝外潜藏、复制、血液传播及肝癌的发病机理等一系列问题都很有意义,本文应用高敏感及特异的聚合酶链反应(PCR)技术,对血清HBsAg阴性的肝癌患者外周白细胞及血清中HBV DNA的存在进行
The relationship between hepatitis B virus (HBV) and primary liver cancer has been recognized. Many studies have confirmed the existence of HBV DNA in hepatoma cells and in various extrahepatic tissues. This is of great significance for a series of problems such as latent extrahepatic HBV replication, blood transmission and the pathogenesis of liver cancer. In this paper, high sensitive and specific polymerase chain reaction (PCR) And the presence of HBV DNA in the serum