[目的]探讨胃肠间质瘤(GIST)所引起相关急腹症的诊治。[方法]对急诊收治入院且病理证实的34例GIST患者的临床表现、检查资料、手术和生存情况进行分析。[结果]34例患者中有消化道出血18例,腹腔出血4例,肠梗阻8例,肿瘤破裂与穿孔4例。29例行根治性切除(90.6%)。3年生存率为88.1%,5年生存率80.4%。[结论]首诊医师应熟悉GIST相关急腹症,早期诊断与手术切除可显著提高患者生存率。 [Objective] To investigate the diagnosis and treatment of related acute abdomen caused by gastrointestinal stromal tumor (GIST). [Methods] The clinical manifestations, examination data, operation and survival of 34 cases of GIST admitted to hospital for emergency treatment were analyzed. [Result] Among the 34 patients, there were 18 cases of gastrointestinal bleeding, 4 cases of abdominal bleeding, 8 cases of intestinal obstruction, 4 cases of tumor rupture and perforation. 29 cases of radical resection (90.6%). 3-year survival rate was 88.1%, 5-year survival rate of 80.4%. [Conclusion] The first visiting physician should be familiar with GIST related acute abdomen, early diagnosis and surgical resection can significantly improve the survival rate of patients.