论文部分内容阅读
恶性肿瘤已是人类三大主要死亡原因之一,是世界上所有国家面临的一个重大健康问题。肿瘤是由各种原因引起多基因损伤和突变积累以及相互作用形成基因调控异常的结果。近几年不少专家发现MicroRNA(一种具有基因转录后调控作用的非编码小分子RNA)与肿瘤的发生、发展、诊断、治疗等有关,可作为一种新的生物标记,被运用于肿瘤的诊断和治疗。本文对MicroRNA在各种肿瘤诊断和治疗等方面的进展作一综述。
Malignant tumors are one of the three major causes of human death and a major health problem facing all countries in the world. Tumor is caused by a variety of causes of multiple gene damage and accumulation of mutations and the formation of interactions as a result of abnormal gene regulation. In recent years, many experts have found that MicroRNA (a non-coding small RNA with the function of gene transcriptional regulation) is related to the occurrence, development, diagnosis and treatment of tumors, and can be used as a new biomarker for cancer Diagnosis and treatment. This article reviews the progress of MicroRNA in the diagnosis and treatment of various tumors.