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目的:探讨单纯良性前列腺增生(BPH)与合并慢性前列腺炎(CP)患者的临床特点及其意义。方法:回顾性分析2011年10月~2013年06月我院泌尿外科行经尿道前列腺等离子电切术(TURP)治疗BPH的患者236例,按照病理诊断分为单纯BPH(35例)和合并CP(201例)两组,采用SPSS 17.0软件进行统计学分析,比较两组患者在年龄、前列腺体积、最大尿流率(Qmax)、剩余尿量(RUV)、国际前列腺症状评分(IPSS)(术前及术后3个月)、生活质量评分(QOL)、是否发生急性尿潴留(AUR)、前列腺特异性抗原(PSA)、前列腺特异性抗原密度(PSAD)等指标上是否存在差异。结果:合并CP组患者在前列腺体积、RUV、IPSS、QOL、AUR发生率等方面指标高于单纯BPH组患者,Qmax低于单纯BPH组,差异有统计学意义。而在年龄及PSA、PSAD等方面指标差异无统计学意义。手术治疗后3个月两组IPSS评分均较术前明显降低,且合并CP组较单纯组评分高,差异均有统计学意义。结论:CP可能是BPH临床进展的重要因素之一,同时也可能是导致BPH患者下尿路症状(LUTS)的重要原因之一。
Objective: To investigate the clinical features and significance of benign prostatic hyperplasia (BPH) and chronic prostatitis (CP). Methods: A retrospective analysis of 236 patients with BPH treated with transurethral resection of the prostate (TURP) in our hospital from October 2011 to June 2013 was divided into three groups: pure BPH (35 cases) and combined CP 201 cases) were divided into two groups and analyzed by SPSS 17.0 software. The difference of age, prostate volume, maximum flow rate (Qmax), residual urine volume (RUV), International Prostate Symptom Score (IPSS) And postoperative 3 months), quality of life (QOL), whether acute urinary retention (AUR), prostate specific antigen (PSA), prostate specific antigen density (PSAD) and other indicators were different. Results: Compared with pure BPH group, the indexes in patients with CP group were significantly higher than those in BPH group in terms of prostate volume, RUV, IPSS, QOL and AUR. Qmax was lower than that of pure BPH group. The difference was statistically significant. There was no significant difference in age, PSA, PSAD and other indicators. Three months after the operation, the IPSS scores of both groups were significantly lower than those before operation, and the scores of IPSS in the combined CP group were higher than those in the simple group, the differences were statistically significant. Conclusion: CP may be one of the important factors in the clinical progress of BPH and may also be one of the important causes of lower urinary tract symptoms (LUTS) in patients with BPH.