甘氨双唑钠(CMNa)联合紫杉醇卡铂化疗对中晚期卵巢癌术后CA125升高的影响(英文)

来源 :Chinese-German Journal of Clinical Oncology | 被引量 : 0次 | 上传用户:freebernie
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Objective:To investigate the effects of CMNa combined with paclitaxel and carboplatin on elevated CA125 levels in post-operation advanced ovarian cancer patients.Methods:The effects of CMNa combined with paclitaxel and carboplatin on elevated CA125 levels in 25 post-operation advanced ovarian cancer patients were retrospectively analyzed and compared with those in 20 control cases.Results:After 1 cycle of chemotherapy,CA125 levels had decreasing trend compared with control,but had no statistical significance.While after two cycles of chemotherapy,CA125 levels decreased more rapidly compared with those in control.Side effects in two groups were alike.Conclusion:CMNa combined with paclitaxel and carboplatine has a stronger effect on the decrease of elevated CA125 levels than paclitaxel and carboplatin have in the treatment of post-operation advanced ovarian cancer,which indicates that CMNa has chemo-sensitizing effects on chemotherapy of paclitaxel and carboplatin. Objective: To investigate the effects of CMNa combined with paclitaxel and carboplatin on elevated CA125 levels in post-operation advanced ovarian cancer patients. Methods: The effects of CMNa combined with paclitaxel and carboplatin on elevated CA125 levels in 25 post-operation advanced ovarian cancer patients were retrospectively analyzed and compared with those in 20 control cases. Results: After 1 cycle of chemotherapy, CA125 levels had decreased trend compared with control, but had no statistical significance. Whilst after two cycles of chemotherapy, CA125 levels decreased more rapidly compared those in control. Side effects in two groups were alike. Confocal: CMNa combined with paclitaxel and carboplatine has a stronger effect on the decreased of elevated CA125 levels than paclitaxel and carboplatin have in the treatment of post-operation advanced ovarian cancer, which indicates that CMNa has chemo-sensitizing effects on chemotherapy of paclitaxel and carboplatin.
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