A series of CoCrFeNb_xNi(x values in molar ratio, x = 0, 0.25, 0.45, 0.5, 0.75, 1.0 and 1.2) high entropy alloys(HEAs) was prepared to investigate the alloying effect of Nb on the microstructures and mechanical properties. The results indicate that the prepared CoCrFeNb_xNi(x > 0) HEAs consist of a simple FCC solid solution phase and a Laves phase. The microstructures of the alloys change from an initial single-phase FCC solid solution structure(x = 0) to a hypoeutectic microstructure(x = 0.25), then to a full eutectic microstructure(x = 0.45) and finally to a hypereutectic microstructure(0.5 < x < 1.2). The compressive test results show that the Nb0.45(x = 0.45) alloy with a full eutectic microstructure possesses the highest compressive fracture strength of 2558 MPa and a fracture strain of 27.9%. The CoCrFeNi alloy exhibits an excellent compressive ductility, which can reach 50% height reduction without fracture. The Nb0.25 alloy with a hypoeutectic structure exhibits a larger plastic strain of 34.8%. With the increase of Nb content, increased hard/brittle Laves phase leads to a decrease of the plasticity and increases of the Vickers hardness and the wear resistance. The wear mass loss, width and depth of wear scar of the Nb1.2(x = 1.2) alloy with a hypereutectic structure are the lowest among all alloy systems, indicating that the wear resistance of the Nb1.2 alloy is the best one. A series of CoCrFeNb_xNi (x values ​​in molar ratio, x = 0, 0.25, 0.45, 0.5, 0.75, 1.0 and 1.2) high entropy alloys (HEAs) was prepared to investigate the alloying effect of Nb on the microstructures and mechanical properties. results indicate that the prepared CoCrFeNb_xNi (x> 0) HEAs consist of a simple FCC solid solution phase and a Laves phase. The microstructures of the alloys change from an initial single-phase FCC solid solution structure (x = 0) to a hypoeutectic microstructure (x = 0.45) and finally to a hypereutectic microstructure (0.5