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目的对比分析不同药物治疗妊娠高血压综合征的临床效果及不良反应。方法选取妊娠高血压综合征患者84例作为研究对象,随机分为2组,每组42例。对照组给予硫酸镁治疗,试验组在对照组治疗的基础上给予酚妥拉明联合硝苯地平治疗。对比2组患者的临床治疗效果及不良反应发生情况。结果试验组总有效率为90.48%高于对照组的73.81%,差异有统计学意义(P<0.05)。试验组治疗后血压及24 h尿蛋白量的改善情况优于对照组,差异均有统计学意义(P<0.05)。试验组宫缩乏力、胎儿宫内窘迫、新生儿窒息、产后出血发生率均低于对照组,差异均有统计学意义(P<0.05)。结论硫酸镁、酚妥拉明及硝苯地平联合治疗妊娠高血压综合征能显著提高患者的临床治疗效果,有效改善患者的各项相关临床指标,且安全可靠,值得临床广泛推广应用。
Objective To compare and analyze the clinical effects and adverse reactions of different drugs in treating pregnancy-induced hypertension syndrome. Methods Eighty-four patients with pregnancy-induced hypertension (Hypertension syndrome) were randomly divided into two groups (42 in each group). The control group was treated with magnesium sulfate. The experimental group was treated with phentolamine combined with nifedipine on the basis of the control group. Comparison of two groups of patients with clinical treatment and adverse reactions occurred. Results The total effective rate of the experimental group was 90.48% higher than that of the control group (73.81%), the difference was statistically significant (P <0.05). The improvement of blood pressure and 24-hour urinary protein after treatment in the experimental group was better than that in the control group, the difference was statistically significant (P <0.05). The incidence of uterine inertia, fetal distress, neonatal asphyxia and postpartum hemorrhage in the experimental group were significantly lower than those in the control group (P <0.05). Conclusion Combination of magnesium sulfate, phentolamine and nifedipine in the treatment of pregnancy-induced hypertension syndrome can significantly improve the clinical therapeutic effect of patients and effectively improve the clinical indicators of patients with safe and reliable, it is worth widely clinical application.