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[目的]观察自拟五虫通络汤联合现代康复治疗急性缺血性脑卒中疗效。[方法]使用随机平行对照方法,将60例住院及门诊患者按随机数字表法随机分为两组。对照组30例西医常规治疗方法,控制脑水肿、抗血小板聚集、控制血压血糖血脂、预防感染等基础治疗措施。治疗组30例自拟五虫通络汤(黄芪30g,当归12g,川芎15g,丹参30g,赤芍15g,桃仁12g,红花12g,全虫10g,水蛭12g,土元12g,白僵蚕12g,地龙15g,络石藤30g,伸筋草30g,鸡血藤30g,钩藤30g,建曲15g,甘草6g),1剂/d,每剂浓缩为两袋,每袋150mL,2次/d,早晚服用。同时在生命体征稳定后早期加现代康复Bobath疗法。西医治疗同对照组。连续治疗30d为1疗程。观测临床症状、NIHSS评分、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组基本痊愈3例,显著进步15例,进步7例,无变化5例,恶化0例,总有效率83.33%。对照组基本痊愈1例,显著进步11例,进步5例,无变化13例,恶化0例,总有效率56.67%。治疗组疗效优于对照组(P<0.05)。两组NIHSS评分有改善(P<0.05,P<0.01),治疗组优于对照组(P<0.01)。[结论]自拟五虫通络汤联合现代康复治疗急性缺血性脑卒中可以较好的提高患者的生活自理能力,减轻后遗症,且安全,有效,经济,值得进一步研究。
[Objective] To observe the curative effect of self-made Wusong Tongluo Decoction combined with modern rehabilitation on acute ischemic stroke. [Methods] Using randomized parallel control method, 60 inpatients and outpatients were randomly divided into two groups according to random number table method. The control group of 30 cases of conventional Western medicine treatment, control of brain edema, anti-platelet aggregation, blood pressure blood lipid control, prevention of infection and other basic treatment measures. In the treatment group, 30 cases of self-made Wusong Tongluo Decoction (Astragalus 30g, Angelica 12g, Chuanxiong 15g, Salvia 30g, red peony 15g, peach kernel 12g, safflower 12g, all insects 10g, leeches 12g, , Earthworm 15g, Luodan 30g, Leptinus 30g, Millettia 30g, Uncaria 30g, song 15g, licorice 6g), 1 / d, each dose is concentrated into two bags, each bag 150mL, 2 times / d, morning and evening. In the meantime, Bobath therapy is added to the early rehabilitation of the vital signs after the stable vital signs. Western medicine treatment with the control group. Continuous treatment of 30d for a course of treatment. Observed clinical symptoms, NIHSS score, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Results] The treatment group basically cured in 3 cases, a significant improvement in 15 cases, advanced in 7 cases, no change in 5 cases, worsening in 0 cases, the total effective rate was 83.33%. The control group basically recovered in 1 case, significantly improved in 11 cases, improved in 5 cases, no change in 13 cases, 0 cases of deterioration, the total effective rate was 56.67%. The treatment group was better than the control group (P <0.05). NIHSS score was improved in both groups (P <0.05, P <0.01), and the treatment group was superior to the control group (P <0.01). [Conclusion] Self-made Wusong Tongluo Decoction combined with modern rehabilitation in the treatment of acute ischemic stroke can better improve patients’ self-care ability and reduce sequelae, and is safe, effective and economical, which deserves further study.