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目的探讨通便玉蓉丸对便秘型小鼠排便功能的影响,以阐明其治疗便秘的机理。方法检测正常小鼠及便秘小鼠的胃排空率、小肠推进率及肠段水分含量。结果通便玉蓉丸促进胃排空作用明显,促进小肠碳末推进作用明显,肠段水分含量增加,与模型组比较,有显著差异(P<0.05)。结论通便玉蓉丸通过提高胃排空率、小肠推进率及大肠吸收水分的作用,能够增加排便治疗便秘。
Objective To investigate the effect of Tongyou Yu Rong Wan on defecation in mice with constipation to clarify the mechanism of constipation. Methods The gastric emptying rate, intestinal propulsion rate and intestinal water content of normal mice and constipation mice were detected. Results Tongmai Yurong Pill had significant effect of promoting gastric emptying, promoting the small intestine promoting carbon end, and increasing the intestine water content. Compared with the model group, there was a significant difference (P <0.05). Conclusions Tongbian Yu Rong Pills can increase defecation to treat constipation by increasing gastric emptying rate, small intestine propulsion rate and absorption of water by the large intestine.