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目的分析2010-2014年哈尔滨市先天风疹综合征(CRS)的监测结果。方法采用描述流行病学方法,对监测的CRS病例进行分析,并对监测指标进行评价。结果 2010-2014年,哈尔滨市共报告CRS疑似病例611例,诊断为CRS的37例,发病率在6.88/10万~15.23/10万之间,年平均发病率为10.05/10万活产儿童;临床表现主要为先天性心脏病、听力损失和眼部疾病,患儿母亲均无明确风疹疫苗接种史;实验室诊断病例感染风疹病毒的时间集中在孕4~6周。结论我市CRS发病率仍在较高水平。应继续加强疫苗接种,开展育龄期妇女血清抗体水平监测,继续开展CRS病例监测,为制定CRS防控策略提供依据。
Objective To analyze the surveillance results of congenital rubella syndrome (CRS) in Harbin in 2010-2014. Methods Using descriptive epidemiological methods, the surveillance of CRS cases were analyzed and the monitoring indicators were evaluated. Results From 2010 to 2014, Harbin reported a total of 611 suspected cases of CRS and 37 cases diagnosed as CRS. The incidence rates ranged from 6.88 / 100000 to 15.23 / 100000 with an average annual incidence of 10.05 / 100000 live births ; The main clinical manifestations of congenital heart disease, hearing loss and eye diseases, mothers have no specific rubella vaccination history; laboratory diagnosis of cases of rubella virus infection time concentrated in 4 to 6 weeks pregnant. Conclusion The incidence of CRS in our city is still at a high level. Should continue to strengthen vaccination, to carry out the monitoring of serum antibody levels in women of childbearing age, continue to carry out monitoring of CRS cases, to provide the basis for the development of CRS prevention and control strategies.