论文部分内容阅读
目的:评价乳酸左氧氟沙星治疗肺部感染性疾病的临床疗效、不良反应和安全性。方法:46 例肺部感染患者(男33 例,女23 例),使用国产乳酸左氧氟沙星,每天2 次,每次0.1g,疗程7~10d;逐日观察症状、体征的改变及不良反应情况,致病菌按NCCLS制定的标准作纸片法药敏试验,并注意药物对肝、肾功能的影响。结果:46 例患者经过治疗,痊愈28 例(60.86% ),显效14 例,(30.44% ),总有效率(痊愈+ 显效)91.3% ,痰菌清除率87.5% ,不良反应发生率为6.5% 。结论:国产乳酸左氧氟沙星临床效果确切,安全性好,适合于各类中、重度肺部感染性疾病的治疗
Objective: To evaluate the clinical efficacy, adverse reactions and safety of levofloxacin lactate in the treatment of pulmonary infectious diseases. Methods: Forty-six patients with pulmonary infection (33 males and 23 females) were treated with levofloxacin lactate twice daily for 0.1-10 days for 7-10 days. The symptoms and signs and the adverse reactions were observed daily Pathogenic bacteria by NCCLS standards for paper-based drug susceptibility testing, and pay attention to the impact of drugs on liver and kidney function. Results: After treatment, 46 cases were cured, 28 cases were cured (60.86%), 14 cases were markedly effective (30.44%), the total effective rate was 91.3%, the sputum bacterial clearance rate was 87.5% and the adverse reaction rate was 6.5% . Conclusion: Domestic levofloxacin lactate clinically effective and safe, suitable for all kinds of moderate and severe pulmonary infectious disease treatment