对30例早产儿预防性应用国产静脉注射丙种球蛋白（IVIG），每天0．4g／kg，首次用后3天重复1次，治疗1周后复查血清Ig水平，IVIG组血清lgG明显升高，峰值为10·48±2．719／L，与对照组及自身对照比较差异均有显著意义，并密切观察其临床疗效，发现IVIG组交叉感染率、病死率都明显下降，未发现近期不良反应，故用国产IVIG预防早产儿感染是安全有效的。 The prophylactic use of intravenous gamma globulin (IVIG) in 30 preterm infants was 0.4g / kg once daily for 3 days after the first use. After 1 week of treatment, serum Ig levels were reexamined and serum lgG in IVIG group was significantly higher , Peak value of 10 · 48 ± 2.719 / L, with the control group and its own control were significantly different, and close observation of its clinical efficacy and found IVIG cross infection rate, mortality were significantly decreased, no recent adverse reactions found Reaction, it is safe to use domestic IVIG prevention of infection in premature children.