建立实验动物脑血栓模型,对探讨缺血性脑损伤的发生机制及对防治脑血栓、脑缺血的相关研究有理论和实践价值。本文对脑血栓动物模型的建模原理及方法进行综述,并对各类模型的优缺点和适用范围等方面进行了初步的分析。力求为选择和建立适于各类脑血栓疾病相关研究的实验动物模型提供参考。 The establishment of experimental animal model of cerebral thrombosis has theoretical and practical value in exploring the mechanism of ischemic brain injury and its prevention and treatment of cerebral thrombosis and cerebral ischemia. This article summarizes the modeling principles and methods of animal model of cerebral thrombosis, and makes a preliminary analysis of the advantages and disadvantages of various models and the scope of application. To seek for the selection and establishment of experimental animal models suitable for all kinds of cerebral thrombosis related studies provide a reference.