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为了研究地榆生肝汤的保肝效果,采用三种药液:F-Ⅰ(以蒸馏水浸出的地榆生肝汤),F-Ⅱ(不含多糖的地榆生肝汤),F-Ⅲ(含多糖的地榆生肝汤)。以四氯化碳和d-氦基半乳糖引起的肝功能损害小鼠作为本次实验的研究对象。结果:①高度浓缩的F-Ⅲ能明显抑制四氯化碳引起肝损害小鼠血清中GOT活性的增加,高度浓缩的F-Ⅰ.F-Ⅲ能明显抑制四氯化碳引起肝损害小鼠GPT.LDH,
In order to study the liver-protective effects of Disheng Shenggan Decoction, three medicinal liquids were used: F-I (Digestive Liver Soup leached with distilled water), F-II (Dioscorean Liver Soup without polysaccharides), F- III (Ganzhi Liver Soup containing polysaccharides). Mice with hepatic impairment induced by carbon tetrachloride and d-decylgalactose were the subject of this experiment. RESULTS: (1) Highly concentrated F-III can significantly inhibit the increase of GOT activity in serum of mice with hepatic impairment induced by carbon tetrachloride. High concentration of F-I.F-III can significantly inhibit carbon tetrachloride-induced liver damage in mice. GPT.LDH,