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海马中富含糖皮质激素受体 ,是应激损伤的主要靶器官。海马突触传递的长时程增强 (LTP)效应可直接反映学习记忆功能的好坏 ,急、慢性应激时 ,过量糖皮质激素对LTP均有损伤作用。
Hippocampus is rich in glucocorticoid receptor, is the main target organ damage. The long-term potentiation (LTP) effect of hippocampal synaptic transmission can directly reflect the learning and memory function. Excess and glucocorticoid can damage LTP in both acute and chronic stress.