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多发性骨髓瘤(MM)是一种起源于浆细胞的血液系统恶性肿瘤,其特征表现为恶性浆细胞在骨髓内克隆性异常增殖,血清中出现单克隆免疫球蛋白和(或)免疫球蛋白轻链。临床上以溶骨性骨病、贫血、肾功能损害、高钙血症为其特征。在血液系统恶性肿瘤中,MM排名第二,约占10%,占所有恶性肿瘤的1%。我国报道MM发病率低于欧美
Multiple myeloma (MM) is a hematologic malignancy that originates from plasma cells characterized by clonally abnormal proliferation of malignant plasma cells in the bone marrow, presence of monoclonal immunoglobulins and / or immunoglobulins in the serum Light chain. Clinically osteolytic bone disease, anemia, renal dysfunction, hypercalcemia is characterized. Among hematological malignancies, MM ranks second, accounting for about 10%, accounting for 1% of all malignancies. The incidence of MM in our country is lower than in Europe and America