一、引言鲎试验是利用一种栖生于海洋中的节肢动物“鲎”的血细胞溶解物(鲎试剂TAL)与微量细菌内毒素发生凝胶反应的一种实验。这是一种体外的生化测定方法,反应速度和凝胶的牢固度与内毒素的浓度相关。目前,许多国家已将鲎试验法用于药品热原和临床快速检验。1980年美国首先将鲎试验以“细菌内毒素试验”条目收载于美国药典(第20版), I. INTRODUCTION 鲎 The test is an experiment that uses a hemolytic substance (鲎 Reagent TAL) of a species of arthropod “鲎” living in the oceans to gel react with trace bacterial endotoxins. This is an in vitro biochemical assay that correlates with the speed of reaction and the firmness of the gel with the concentration of endotoxin. At present, many countries have adopted the test method 药 pyrogen and clinical rapid test drugs. In 1980, the United States first 鲎 test with “bacterial endotoxin test” entry contained in the United States Pharmacopoeia (20th edition),