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对325例不同胃部疾患者的胃粘膜活检材料进行CP镜检和脲酶活性测定,结果证明幽门弯曲杆菌是胃部疾患的常见细菌,特别是慢性活动性胃炎CP的阳性率高达89％,脲酶活性升高达90％,进而用能杀灭CP的铋制剂对CP阳性(+++++)且脲酶活性阳性(10min内显反应)的慢性活动性胃炎患者进行治疗,在一个疗程后症状明显减轻或消失,此时镜检CP阳性率和脲酶活性均明显下降。就每一病例而言,CP的减少和脲酶活性的下降完全一致,因此建议用简便易行的脲酶活性检查代替CP镜检,这在胃部疾患的CP研究中是适宜的。
The microscopic examination of gastric mucosal biopsy material and urease activity in 325 gastric patients with different stomach diseases showed that Campylobacter pylori was a common bacteria in gastric diseases, especially the positive rate of CP in chronic active gastritis was as high as 89%. Urease Activity increased up to 90%, and then with bismuth can kill the CP positive CP positive (++++) and urease activity positive (10min significant reaction) of chronic active gastritis patients treated after a course of symptoms were obvious Reduce or disappear, then the positive rate of microscopic examination CP and urease activity were significantly decreased. For each case, the decrease in CP was in complete agreement with the decrease in urease activity, so a simple and convenient test for urease activity instead of microscopic examination of CP was recommended, which is appropriate in CP studies of gastric disorders.