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目的探析于输卵管妊娠患者中行腹腔镜输卵管切除术对患者生殖功能的影响。方法 110例输卵管妊娠患者,随机分为对照组(50例)和实验组(60例)。对照组行腹腔镜保留患侧输卵管的手术,实验组行腹腔镜输卵管切除术。对比两组患者性激素指标及随访结果。结果实验组患者术后各时段促黄体生成素(LH)和卵泡刺激素(FSH)水平均显著优于对照组,差异具有统计学意义(P<0.05);实验组术后1、3个月抗苗勒管激素(AMH)和雌二醇(E_2)水平明显低于对照组,差异具有统计学意义(P<0.05);两组患者术后6个月AMH和E_2水平比较差异无统计学意义(P>0.05)。两组患者术后6个月排卵率、术后2年妊娠率对比差异无统计学意义(P>0.05);实验组患者术后2年异位妊娠率为6.67%,明显低于对照组的20.00%,差异具有统计学意义(P<0.05)。结论于输卵管妊娠患者中行腹腔镜输卵管切除术对患者生殖功能有负面影响,但其可使再次异位妊娠的发生率显著降低。是否要对患者进行输卵管切术后,需视患者的生育需求与输卵管实际情况而定。
Objective To investigate the effect of laparoscopic tubal resection on reproductive function in patients with tubal pregnancy. Methods 110 patients with tubal pregnancy were randomly divided into control group (50 cases) and experimental group (60 cases). The control group laparoscopic surgery to retain the ipsilateral fallopian tubes, the experimental group underwent laparoscopic tubal resection. The two groups of patients with sex hormone index and follow-up results. Results The levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in the experimental group were significantly higher than those in the control group at each time point after operation, the difference was statistically significant (P <0.05) The levels of anti-Mullerian hormone (AMH) and estradiol (E_2) in the two groups were significantly lower than those in the control group (P <0.05). There was no significant difference in AMH and E_2 levels between the two groups Significance (P> 0.05). The ovulation rate at 6 months after operation and pregnancy rate at 2 years after operation showed no significant difference (P> 0.05). The rate of ectopic pregnancy at 2 years after operation in the experimental group was 6.67%, which was significantly lower than that in the control group 20.00%, the difference was statistically significant (P <0.05). Conclusions Laparoscopic tubal surgery in patients with tubal pregnancy has a negative impact on reproductive function in patients, but it can significantly reduce the incidence of ectopic pregnancy again. Whether patients should undergo tubal surgery, depending on the patient’s reproductive needs and fallopian tube actual conditions.