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氯霉素是一种广谱抗生素,因其抗菌效果好且价格低廉而被广泛用于畜牧养殖业,但对人体有不良反应,主要是引起人类骨髓功能抑制,从而导致再生障碍性贫血、血小板减少性紫癜等疾病。目前,我国已禁止在动物性食品生产过程中使用氯霉素,但私自使用的现象仍然存在,这就使氯霉素有可能残留在动物性食品中进而对人体健康构成危害。目前用于氯霉素残留的检测方法主要有:微生物法、免疫学法、气相色谱、液相色谱、气质联用及液质联用等,其中微生物及免疫学法常作为初步筛选实验;色谱法作为确证及定量方法;气质联用与液质联用为我国国标中氯霉素残留检测方法。
Chloramphenicol, a broad-spectrum antibiotic, is widely used in livestock husbandry because of its good antibacterial effect and low price. However, chloramphenicol has adverse reactions to human body and mainly causes inhibition of human bone marrow function, resulting in aplastic anemia, platelet Reduce purpura and other diseases. At present, China has banned the use of chloramphenicol in the production of animal foods, but the phenomenon of unauthorized use still exists, which makes it possible for chloramphenicol to remain in animal foods and thus endanger human health. Currently used for detection of chloramphenicol residues are: microbial method, immunological methods, gas chromatography, liquid chromatography, GC-MS and LC-MS, among them microbial and immunological methods often as a preliminary screening experiment; chromatography France as a confirmatory and quantitative methods; GC-MS and LC / MS for China's national standard chloramphenicol residue detection method.