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目的：研究非糖尿病腹膜透析患者高尿酸血症与代谢综合征（M S ）的关系。方法检测97例规律腹膜透析的非糖尿病患者的血清尿酸水平，依据调整后的美国胆固醇教育计划成人治疗组第三次报告指南标准诊断M S ，采用Logistic多因素回归分析M S的危险因素。结果97例非糖尿病腹膜透析患者 MS 的发病率为45.4％，高尿酸血症患者 MS 的发病率更高（χ2＝3.950， P＜0．05）。多因素Logistic回归分析显示，血清尿酸（OR＝2.142）、BMI（OR＝1.498）、TG（OR＝6.074）、HDL‐C（OR＝0.039）和 FBG（OR ＝2.384）水平是 MS的独立影响因素（P＜0．05）。结论非糖尿病腹膜透析患者MS发病率高，高尿酸血症是MS的独立危险因素。“,”Objective To investigate the relationship between hyperuricemia and metabolic syndrome in non‐diabetic patients undergoing peritoneal dialysis .Methods Serum level of uric acid was detected in 97 non‐diabetic patients undergoing regular peritoneal dialysis .Metabolic syndrome was diagnosed according to adjusted US National Cholesterol Education Program Adult Treatment Panel Ⅲ criteria .The risk factors for metabolic syndrome were analyzed using multivariate logistic regression analysis .Results The incidence of metabolic syndrome in the 97 patients was 45.4% .The incidence of metabolic syndrome was higher in the patients with hyperuricemia than that in those without hyperuricemia (χ2 = 3.950 ,P<0 .05) .Multivariate logistic regression analysis showed that serum uric acid(OR=2.142) ,body mass index(OR=1.498) ,triglyceride(OR=6.074) ,high‐density lipoprotein(OR= 0.039) ,and fasting blood glucose (OR = 2.384) were the independent influence factors for metabolic syndrome(P<0 .05) .Conclusion Non‐diabetic patients undergoing peritoneal dialysis exist a higher incidence of metabolic syndrome ,in whom hyperuricemia is an independent risk factor for metabolic syndrome .