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目的:探讨曲美他嗪联合阿托伐他汀治疗冠心病心绞痛的临床效果。方法:选择我院内科2009年5月至2011年5月收治的冠心病心绞痛患者40例,随机分为两组,对照组20例采用曲美他嗪治疗,观察组20例在此基础上加用阿托伐他汀治疗,就两组的临床资料进行回顾性分析。结果:两组治疗前的肌酐、心功能相关指标比较无明显差异(P>0.05)。治疗后观察组的相关指标情况均优于对照组,差异有统计学意义(P<0.05)。观察组20例患者中,显效14例,占70%;有效5例,占25%;无效1例,占5%,临床有效率为95%。对照组20例患者中,显效10例,占50%;有效6例,占30%;无效4例,占20%,观察组临床有效率明显优于对照组(P<0.05)。结论:应用阿托伐他汀联合曲美他嗪治疗冠心病心绞痛,可显著改善心功能,提高临床效果,进而改善患者的生存质量。
Objective: To investigate the clinical effect of trimetazidine and atorvastatin in the treatment of angina pectoris. Methods: Forty patients with coronary heart disease and angina pectoris admitted from May 2009 to May 2011 in our hospital were randomly divided into two groups. In the control group, 20 patients were treated with trimetazidine. In the observation group of 20 patients, With atorvastatin treatment, the clinical data of two groups were retrospectively analyzed. Results: There was no significant difference between the two groups in creatinine and cardiac function before treatment (P> 0.05). After treatment, the relevant indicators of the observation group were better than the control group, the difference was statistically significant (P <0.05). Among the 20 patients in the observation group, 14 were markedly effective, accounting for 70%; 5 were effective, accounting for 25%; 1 was ineffective, accounting for 5%, and the clinical effective rate was 95%. The control group of 20 patients, markedly effective in 10 cases, accounting for 50%; effective in 6 cases, accounting for 30%; ineffective in 4 cases, accounting for 20%, the clinical efficiency of the observation group was significantly better than the control group (P <0.05). Conclusion: Atorvastatin combined with trimetazidine in the treatment of coronary heart disease angina pectoris can significantly improve cardiac function, improve clinical efficacy, and then improve the quality of life of patients.