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对具有不同程度听力损伤患者(共20例耳),在不脱产情况下,口服赛鲨力补氧胶囊25天(11.2g/d),观察治疗前后其听力和静脉血中的铜蓝蛋白酶、超氧化物歧化酶(SOD)活性及过氧化脂质(LPO)含量的变化。结果表明,口服赛鲨力补氧胶囊后,患者静脉血中的铜蓝蛋白酶、超氧化物歧化酶活性显著升高:语频段听力恢复的有效率为71.4％,高频有效率为78.9％。因此,鲨烯不仅可以改善体内的代谢物清除水平,而且能够显著改善职业性噪声导致的听力损伤。
To patients with varying degrees of hearing impairment (a total of 20 ears), without giving birth, shark force supplement capsules oxygen 25 days (11.2g / d), before and after treatment to observe the hearing and venous blood of ceruloplasmin, Changes of superoxide dismutase (SOD) activity and lipid peroxidation (LPO) content. The results showed that the activity of copper-blue proteinase and superoxide dismutase in venous blood of patients with oral shark-force capsules increased significantly: the effective rate of hearing recovery in speech frequency was 71.4% and the high-frequency efficiency was 78.9%. Therefore, squalene not only improves metabolite clearance in the body, but also significantly improves hearing impairment caused by occupational noise.