Crosslinked chitosan resin is a new type of billrubin adsorbent.It can adsorb boththe conjugated and unconjugated bilirubin- Adsorption experiments were performed byadding the resins to previously prepared bilirubin solution, with different concentrations ofbilirubin and BSA. The dissociation equilibrium constant and conJugated free energy for thebilirubin-albumin complex were obtained according to plot. Crosslinked chitosan resin is a new type of billrubin adsorbent. It can adsorb both the conjugated and unconjugated bilirubin-Adsorption experiments were performed byadding the resins to previously prepared bilirubin solution, with different concentrations of bilirubin and BSA. The dissociation equilibrium constant and conJugated free energy for the bilirubin -albumin complex were obtained according to plot