论文部分内容阅读
目的对糖尿病合并高脂血症进行临床观察与分析,以期提高对二者合并的认识、延缓并发症的出现。方法于2010年2月至2011年3月选取68例糖尿病合并高脂血症患者且于同期选取35例进行健康体检者和43例单纯糖尿病者进行对照,同时对不同人群血液流变学指标、颈动脉硬化情况进行观察与相关数据统计分析。结果糖尿病合并高脂血症者全血高切黏度、全血低切黏度、血浆黏度、颈总动脉、颈内动脉的内径及内-中膜厚度分别与单纯糖尿病者相比P>0.05,而全血中切黏度相比P>0.05;单纯糖尿病者全血高切粘度、全血中切粘度、全血低切粘度、血浆粘度、颈总动脉、颈内动脉的内径及内-中膜厚度分别与健康体检者相比P>0.05。结论糖尿病、高脂血症均是导致动脉粥样硬化的独立危险因素,而二者合并时更是促进动脉粥样硬化、导致血管闭塞的高危因素。
Objective To investigate the clinical observation and analysis of diabetes mellitus and hyperlipidemia in order to raise awareness of the combination of the two and delay the occurrence of complications. Methods Sixty-eight patients with diabetes mellitus and hyperlipidemia were selected from February 2010 to March 2011 and 35 healthy controls and 43 patients with simple diabetes were enrolled in the same period. Blood rheology, Carotid atherosclerosis were observed and related data statistical analysis. Results High blood viscosity, whole blood low viscosity, plasma viscosity, carotid artery, internal carotid artery internal diameter and intima-media thickness in diabetic patients with hyperlipidemia were significantly higher than those in patients with simple diabetes mellitus Whole blood shear viscosity compared to P> 0.05; simple diabetic patients with high blood viscosity, blood viscosity, whole blood low shear viscosity, plasma viscosity, common carotid artery, internal carotid artery diameter and intima-media thickness Respectively, compared with healthy subjects P> 0.05. Conclusions Both diabetes and hyperlipidemia are independent risk factors of atherosclerosis, and the combination of them is also a risk factor for promoting atherosclerosis and vascular occlusion.