本文综述β阻滞剂的电生理性能,对其抗心律失常作用的某些可能机理进行讨论。β-肾上腺素能刺激的电生理效应已知β-肾上腺素能刺激对心室组织的电生理效应简述如下。儿茶酚胺对心室组织的作用与所用儿茶酚胺浓度、引起α-肾上腺素能刺激的程度,以及心室肌纤维正常与否有关。细胞作用在正常浦顷野纤维,β-肾上腺素能刺激不改变静息跨膜电位(RMP)、动作电位(AP)相0和相1或传导速度;但影 This review summarizes the electrophysiological properties of beta blockers and discusses some possible mechanisms for their antiarrhythmic effects. Electrophysiological effects of β-adrenergic stimulation It is known that the electrophysiological effects of β-adrenergic stimulation on ventricular tissue are summarized as follows. The effect of catecholamines on ventricular tissue is related to the concentration of catecholamines used, the extent of α-adrenergic stimulation, and whether or not ventricular myocytes are normal. Cells functioned in normal Umbelliferae fibers, and β-adrenergic stimulation did not alter resting transmembrane potential (RMP), action potential (AP) phase 0 and phase 1 or conduction velocity; however,