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多发性肌炎和皮肌炎(以下总称为多发性肌炎)有时合并明显的末梢神经损害,另外,在不伴有明显末梢神经损害的一般的多发性肌炎,肌肉活检时也常见到神经原性改变。但尚无深入研究的报导。作者等根据临床表现、血液学检查、肌肉活检诊断为多发性肌炎47例,对其活检肌肉的神经原性改变的频度、种类、程度进行了探讨。男性15例,女性32例,年龄为3～77岁。按Walton和Adams分类,Ⅰ型(临床症状局限于肌肉的多发性肌炎)21例,Ⅱ型(肌力明显减弱伴轻度皮肤症状和胶原病样症状)13例,Ⅲ型(肌力轻度减弱伴严重的胶原病或皮肤症状)6例,Ⅳ型(并发恶性肿瘤)5例。全部病例皆取肱二头肌、股四头肌进行肌肉活检,作HE染色、Gomori三色染色、NADH染色、常规
Polymyositis and dermatomyositis (hereinafter collectively referred to as polymyositis) sometimes include significant peripheral nerve damage, and neurogenicity is also commonly seen in muscle biopsies of general polymyositis without obvious peripheral nerve damage change. However, no in-depth study has been reported. According to the clinical manifestations, hematology examination, muscle biopsy diagnosed as polymyositis in 47 cases, the frequency of their neurological changes in the muscle, type, degree were discussed. 15 males and 32 females, aged 3 to 77 years old. According to Walton and Adams classification, type I (clinical symptoms confined to muscle polymyositis) in 21 cases, type II (muscle weakness with mild symptoms of skin and collagen-like symptoms in 13 cases, type III Degree of weakness with severe collagen disease or skin symptoms) in 6 cases, type Ⅳ (concurrent malignant tumors) in 5 cases. All cases were taken biceps, quadriceps muscle biopsy for HE staining, Gomori trichrome staining, NADH staining, conventional