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目的:探讨平均血小板体积(MPV)与活动期炎症性肠病(IBD)的关系,评价其作为IBD活动期标志物的临床价值.方法:对比IBD活动期与缓解期MPV变化,并与红细胞沉降率和C-反应蛋白比较.结果:IBD活动期MPV明显低于缓解期(P<0.01).MPV与红细胞沉降率和C-反应蛋白均呈负相关(分别为r=-0.31,P<0.05和r=-0.37,P<0.01).结论:MPV变化与IBD病情轻重有密切关系.MPV检测有助于临床判断IBD活动期与缓解期,是一个较实用的参考指标.
Objective: To investigate the relationship between mean platelet volume (MPV) and active inflammatory bowel disease (IBD) and to evaluate its clinical value as an active marker of IBD.Methods: The changes of MPV in active and remission stages of IBD were compared with those of erythrocyte sedimentation (P <0.01) .MPV was negatively correlated with erythrocyte sedimentation rate and C-reactive protein (r = -0.31, P <0.05, respectively) And r = -0.37, P <0.01) .Conclusion: The change of MPV is closely related to the severity of IBD.MPV detection is helpful to judge IBD activity and remission in clinic, which is a practical reference index.