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狼疮性肾炎(LN)通常与抗-DNA抗体有关,但根据洗脱物的研究结果,似乎其他的抗原抗体反应,如一些包括抗-Ro/SS-A,mRNP和(或)Sm抗体可能在LN的发病机理中也起一定作用。在本研究发现并进一步研究了存在于黑人女性LN患者的一种特有的沉积素谱。根据1982年美国风湿病学会修订的SLE诊断标准诊断SLE及是否患有肾炎。利用沉积素测定及定量ELISA法检测抗RNA蛋白抗原的抗体,分别采用放免法,短膜虫法,间接免疫荧光法和ELISA法检测抗-ssDNA、ds-DNA抗体,抗核抗体(ANA)和抗磷脂抗体。
Lupus nephritis (LN) is usually associated with anti-DNA antibodies, but according to the eluate study, it appears that other antigen-antibody reactions, such as some including anti-Ro / SS-A, mRNP and / or Sm antibodies, The pathogenesis of LN also plays a role. In this study, we found and further studied a unique deposit spectrum of LN present in black women. According to the 1982 American College of Rheumatology revised SLE diagnostic criteria for the diagnosis of SLE and whether suffering from nephritis. The anti-RNA, anti-ssDNA and anti-nuclear antibody (ANA) were detected by immunoprecipitation, indirect immunofluorescence and ELISA respectively using sediment assay and quantitative ELISA. Antiphospholipid antibodies.